Which base pairs with cytosine in DNA?

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Multiple Choice

Which base pairs with cytosine in DNA?

Explanation:
In DNA, bases pair specifically to keep the double helix uniform and enable accurate replication. Cytosine pairs with guanine because they fit together through hydrogen bonding and shape: cytosine is a pyrimidine and guanine a purine, so their pairing maintains a constant helix width. They form three hydrogen bonds, which strengthens the connection between strands. Adenine pairs with thymine, not cytosine, for the same reason that the pairing must balance hydrogen-bonding patterns and molecular sizes. So the base that pairs with cytosine is guanine.

In DNA, bases pair specifically to keep the double helix uniform and enable accurate replication. Cytosine pairs with guanine because they fit together through hydrogen bonding and shape: cytosine is a pyrimidine and guanine a purine, so their pairing maintains a constant helix width. They form three hydrogen bonds, which strengthens the connection between strands. Adenine pairs with thymine, not cytosine, for the same reason that the pairing must balance hydrogen-bonding patterns and molecular sizes. So the base that pairs with cytosine is guanine.

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